Genome Science and Medicine
Social Cooperation Research Departments
Dissect biomedical phenomena with advanced genomic technologies
We are working with systems biology and medicine to understand complex biological systems through a functional genomics approach. High throughput technology and novel algorithms are required for collecting, integrating, and visualizing the enormous amount of data on gene expression, protein expression, and protein interactions.
- 1)Cancer genomics medicine
Through the mining of driver gene mutations and abnormal gene expression in DNA and RNA in clinical tumor samples, we are developing an accurate method to detect the druggable aberrations for “precision genomic medicine”. - 2)Functional analysis using 3D cell culture system
We aim to elucidate the mechanisms of cell-cell interactions, heterogeneous response to tissue microenvironment, and therapeutic resistance by performing single cell analysis with spatial information using three-dimensional cell culture systems (organoids), which can reproduce in vivo phenomena in vitro as much as possible.
Genome Science and Medicine Laboratory was established as a social collaboration division in the Department of Genome Science & Medicine.
cancer genome profiling
single cell analysis using organoid models
Cooperation Company/Organization
・Chugai Pharmaceutical Co., Ltd.
Member
Senior Research Fellow
Hiroyuki ABURATANI
Project Associate Professor
Genta NAGAE
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