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Researcher's Profile

Project Lecturer

Takeshi SAKURAI

Intelligent Cooperative Systems

E-mail: sakurai.brain.imi.i.u-tokyo.ac.jp

Office:

Tel: 03-5452-5197

FAX: 03-5452-5197

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Biography

2005.03
PhD. Graduate School of Agriculture, Kyoto University
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2005.04
Postdoctoral researcher, Graduate School of Information Science and Technology, The University of Tokyo (UTokyo)
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2006.04
Postdoctoral researcher, Research Center for Advanced Science and Technology (RCAST), UTokyo
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2006.07
Postdoctoral researcher, RCAST, UTokyo
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2007.05
Project Research Associate, RCAST, UTokyo
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2013.12
Project Lecturer, RCAST, UTokyo

Research Interests

The atmosphere contains various volatiles that can cause health problems. Development of odorant sensors that can detect such harmful volatiles accurately and instantly even at low concentrations is important to build a safe society. Such odorant sensors would also have various other uses, such as finding people buried in disasters, detecting drugs at airports, finding explosive substances in places such as mines, and so on. These various needs have pushed an increasing interest in odorant biosensors that utilize the molecular mechanisms of biological olfactory detection systems, which are superior to existing odorant sensors in terms of sensitivity, selectivity, range of detectable odorants, and so on. Insects have simple and sophisticated olfactory systems that meet the above-mentioned characteristics. Therefore, we are currently using transgenic and genome editing techniques to focus on analyzing the molecular mechanisms underlying the highly specific and sensitive odorant detection in insects. We are working to develop odorant sensor elements whose performance is comparable to insect olfactory systems by reconstructing the mechanisms in cultured cell lines and/or on artificial membranes.


Keywords

olfaction, pheromone, odorant receptor, odorant sensor, insect, silkmoth

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