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- Kazuki KATO
Researcher's Profile
- Lecturer
- Kazuki KATO
- Structural Biology
- kazukikato
g.ecc.u-tokyo.ac.jp
- Tel
- 03-5452-5400
Biography
| March 2015 | PhD, Department of Biological Sciences, Graduate School of Science, The University of Tokyo |
|---|---|
| April 2015 | Discovery Biologics Dept., Research Div., Chugai Pharmaceutical Co., Ltd. |
| April 2018 | Boston Children's Hospital/Harvard Medical School Research Fellow |
| January 2021 | Project Assistant Professor, RCAST, UTokyo |
| June 2022 | Project Lecturer, RCAST, UTokyo |
| May 2023 | Lecturer, RCAST, UTokyo (-May 2023) |
Research Interests
Self and non-self discrimination is a fundamental principle of the immune response against foreign pathogens such as virus. In higher eukaryotes, pattern recognition receptors detect early pathogen invasion and activate appropriate immunological responses. In prokaryotes, CRISPR-Cas adaptive immune system detects phage virus infection. My group uses structural biology, biochemistry and cell biology to understand molecular mechanisms for those immune systems.
Our current research focuses on
- Structural and functional analysis of newly identified CRISPR-Cas enzyme
- Development of new applications using CRISPR-Cas enzyme
- Regulation of antiviral immune system in higher eukaryote
- Three dimensional structure of CRISPR-Cas7-11 enzyme
- Group photo
Keywords
Innate immunity, Adaptive immunity, Virus, Antibody drug
Educational Systems
- Department of Chemistry and Biotechnology, Graduate School of Enginnering
