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Researcher's Profile

  • Project Lecturer
  • Mitsuhiro NISHIMOTO
  • Clinical Epigenetics

Biography

March 2004 (M.D.) Graduated from Faculty of Medicine, the University of Tokyo (UTokyo)
April 2004 Resident, the University of Tokyo Hospital
June 2005 Resident, Intrernational University of Health and Welfare, Mita Hospital
April 2006 Senior Resident, Division of Endocrinology and Metabolism, Department of Internal Medicine, Showa General Hospital
October 2006 Senior Resident, Department of Nephrology and Endocrinology, the University of Tokyo Hospital
March 2011 (Ph.D.) Graduate school of medicine, UTokyo
April 2012 Project Researcher, the Division of Clinical Epigenetics, RCAST, UTokyo
April 2018 Project Research Associate, the Division of Clinical Epigenetics, RCAST, UTokyo
January 2020 Project Lecturer, the Division of Clinical Epigenetics, RCAST, UTokyo
March 2020 Move Out

Research Interests

Metabolic syndrome is one of the most important clinical problems relating to the cardiovascular death. Life style, including diet, exercise, and alcohol intake, plays a pivotal role in onset and progress of metabolic syndrome. But the impact on the diseases of these factors varies widely among individuals. Metabolic diseases, including obesity, diabetes, and hypertension, induce the irreversible damage to the various organs progressively, although the short-term effects of them are limited. Our purpose is to clarify the mechanisms of metabolic diseases and the progression of the tissue damages, especially the mechanism of the salt-sensitive hypertension and the progression of the tissue damages induced by hypertension and diabetes by investigating the effects of steroid hormones, obesity, aging, and prenatal conditions.

Keywords

Hypertension, salt, renin-anigiotensin-aldostereone system, epigenetics

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