Researcher's Profile

  • Professor
  • Hideaki KATO
  • Structural Bioengineering
E-mail
c-hekatog.ecc.u-tokyo.ac.jp
Tel
03-5452-5117
URL

Laboratory HomepageOpen a new window

Biography

                        
March 2009 B.Sc., School of Science, The University of Tokyo (UTokyo)
March 2014 Ph.D., Department of Biophysics and Biochemistry, School of Science, UTokyo
April 2014 Postdoctoral fellow, Department of Biophysics and Biochemistry, School of Science, UTokyo
May 2014 Postdoctoral fellow, Department of Molecular and Cellular Physiology, School of Medicine, Stanford University
April 2019 Associate Professor, Department of Life Sciences, School of Arts and Sciences, UTokyo
February 2024 Professor, RCAST, UTokyo

Research Interests

Our laboratory is primarily dedicated to exploring the molecular mechanisms through which living organisms receive and convert a broad spectrum of physical and chemical stimuli, including light, magnetic fields, and heat, at the atomic level. We employ a combination of structural, biophysical, biochemical, and electrophysiological techniques to unravel how the responsible proteins function. Leveraging our insights into these mechanisms, we also aim to develop novel proteins with modified properties (research tool development) and small molecules and peptides with beneficial therapeutic properties (drug development) using structure- and AI-guided approaches.




Structure-guided engineering of optogenetics and chemogenetics tools

Award

  • June 2012 Young Scientist Award from Protein Science Society of Japan
  • August 2012 The Merck Award for Young Biochemistry Researcher
  • November 2013 The JSPS Ikushi Prize
  • March 2014 University of Tokyo Graduate School of Science Research Award
  • March 2014 University of Tokyo Graduate School of Science President's Award
  • September 2015 Young Scientist Award of the Biophysics Society of Japan 2015
  • July 2016 SPRUC Young Scientist Award
  • December 2016 Inoue Research Award for Young Scientists
  • December 2019 Ministry of Education, Culture, Sports, Science and Technology, NISTEP Selection Award
  • April 2020 The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology, The Young Scientists’ Award
  • September 2020 Frontier Salon Nagase Prize, Special Prize
  • December 2020 Shimadzu Young Researcher Award

Keywords

Structural Biology, Cryo-electron microscopy, Protein design, Optogenetics, Magnetogenetics, Drug discovery, Rhodopsins, GPCRs

Educational Systems

  • Department of Biological Sciences, Graduate School of Science
  • Department of Advanced Interdisciplinary Studies, Graduate School of Engineering

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