Researcher's Profile

  • Emeritus Professor
  • Takao HAMAKUBO


April 1987 Instructor, Dept. of Clinical Science and Lab. Medicine, Kyoto University Faculty of Medicine
March 1993 Research Instructor, Dept of Biochemistry, Vanderbilt University School of Medicine, USA
February 1995 Instructor, Dept of Medical Science, Kyoto University
May 1996 Instructor, RCAST, The University of Tokyo (UTokyo)
October 1997 Lecturer, RCAST, UTokyo
April 1999 Associate Professor, RCAST, UTokyo
April 2002 Professor, RCAST, UTokyo (~March 2018)
June 2018 Emeritus Professor, UTokyo

Research Interests

The objective of our research is to find a new therapeutic strategy for cancer and severe inflammatory diseases through understanding the biological phenomena in dynamic molecular interactions. Our challenges in the quantitative biological approaches are the establishment of FRET (fluorescent resonance energy transfer) probe of GPCR (G-protein coupled receptor) signaling for live cell imaging of chemotaxis, the computer-assisted drug design based on the protein structure and thermodynamic analysis of protein interactions for the cancer treatment, the development of water-window X-ray microscope, the molecular pattern recognition analysis in the host defense mechanism in innate immunity, and the protein – RNA interactions in the regulation of RNA splicing related to the cell cycle control.


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