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Networked Biophotonics Ota Laboratory

Networked Biophotonics
Ota Laboratory

Explore life science beyond human limit by networking optics, microfluidics, genomics & information technologies

The Thinking Machines

Our ultimate ambition is to create a machine that can think independently and make crazy discoveries in domains like Physics, Biology, and Medicine.To this goal, we invent new physical tools to probe biological structures and develop ways of networking biological measurements using the world’s best technologies. Our research spans a wide spectrum of applications, from fundamental scientific inquiry to transformative solutions in the healthcare and industrial sectors.

Bridging Measurements

Harnessing expertise in optics, microfluidics, electronics, chemistry, genomics, and engineering, we develop integrative systems that seamlessly network biological measurements. These platforms enable the interrogation of complex living systems by leveraging the power of data science, including advanced machine learning.

Bridging Biological and Physical Sciences

Biological systems are inherently complex, often resisting description through physical frameworks. For instance, understanding how non-molecular factors influence biological outcomes. By advancing the engineering of quantitative biology, we are developing novel approaches to address this gap—exploring new possibilities for these phenomena and translating our discoveries into impactful healthcare innovations.

Advancing Biophotonics, Microfluidics, and Information Technologies

In pursuit of the grand challenges outlined above—and through independent exploration—we are dedicated to developing novel optical imaging methods, functional micro/nanofluidic systems, and advanced information technologies. We also focus on integrating these modalities to create powerful, multifunctional platforms.
Through this scientific journey, new technologies continuously emerge, often sparking opportunities for industrial innovation and opening exciting frontiers for real-world impact

Machine Learning-driven imaging cell sorter
Temporal tracking of single cell-derived extracellular vesicles
High throughput and high-dimensional cytometry

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Ota Lab is a dynamic environment where members from diverse backgrounds and interests come together to leverage one another’s strengths, learn collaboratively, and spark cross-disciplinary innovation. Our mission is to pioneer the next generation of biotechnology, biomedicine, and biophysics by nurturing individual expertise while courageously working across boundaries to solve complex challenges.
We place a strong emphasis on proactive communication, embracing digital tools to share ideas and collectively address problems. At the same time, we value the power of in-person dialogue and spontaneous idea exchange.
As a lab leader, I make it a priority to be actively present, engaging with members and wish to directly to experiments being on the work bench.Together, with dedication and joy, we strive to push the frontiers of research and discovery.

Member

- Professor
  Sadao OTA
Research Area：Optical Imaging, Microfluidics, Bioengineering, Information Technology, Technology Networking

- Project Research Associate
  Kazuki HATTORI
Research Area：Organoid, Cell signaling, microfluidics

- Project Research Associate
  Akihiro EGUCHI
Research Area：Cell Signaling, Bioengineering,Proteomics, Chemical Biology

Laboratory Homepage

https://sadaotalab.com/

＜As of October 2025＞

Networked Biophotonics Ota Laboratory