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Researcher's Profile

  • Fellow
  • Tadatsugu TANIGUCHI
  • RCAST Fellow
E-mail
tadam.u-tokyo.ac.jp
Tel
03-5452-6492
FAX
03-5452-6493
URL

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Biography

November 1978 Member, Cancer Institute, Japanese Foundation for Cancer Research
October 1979 PhD, University of Zurich
April 1984 Professor, Institute for Molecular and Cellular Biology, Osaka Uiversity
January 1995 Professor, The University of Tokyo (UTokyo) School of Medicine
April 2012 Project Professor, Institute of Industrial Science, UTokyo
April 2019 Advisor to the Office of President, The University of Tokyo
April 2021 Fellow, RCAST, UTokyo

Research Interests

My work principally concerns the mechanisms of signal transduction and gene expression that underlie immunity and oncogenesis. Many of his research projects have stemmed from his original discovery of two cytokine genes, interferon-beta and interleukin-2. These discoveries have laid the groundwork for the molecular characterization of the various systems of cytokines as well as therapeutic advances achieved by the administration of cytokines. One extension of this research was his discovery of a new family of transcription factors, the interferon regulatory factors (IRFs), which he and others have since identified as playing integral roles in the regulation of the immunity, inflammation and cancer. My curent interest is to clarify underlying mechanisms of how the immune system affects cancer.

Keywords

Inflammmation, Immunity, Cancer

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