- Project Professor
- Toshiya TANAKA
- Integrative Nutriomics and Oncology
|March 1993||M.S. Tokyo University of Pharmacy and Life Science|
|April 1993||Research & Development Divisiton, Grelan Pharmaceutical Co., Ltd.|
|September 2004||Ph.D. The University of Tokyo(UTokyo)|
|October 2004||Project Assistant Professor, RCAST, UTokyo|
|February 2006||Project Associate Professor, RCAST, UTokyo|
|April 2007||Project Associate Professor, RCAST, UTokyo|
|April 2015||Project Professor, RCAST, UTokyo|
Protein tissue and cellular localization data provide valuable information helpful in elucidating physiological function. By immunohistochemical analyses, we determine the tissue and cellular localization of all 48 members of NRs protein.
ChIP-sequencing of nuclear receptors
We perform ChIP-sequencing to identify genomic NRs binding sites. This method has the advantage of identifing direct interactions between NRs and their responsive elements.
Targeted proteomics of nuclear receptors
Protein-protein interactions regulate NRs transcriptional activity and their target genes expression levels. We utilize a shotgun proteomics technique to identify NRs complex formation.